Tauroursodeoxycholic acid (TUDCA) enhanced intracytoplasmic sperm injection (ICSI) embryo developmental competence by ameliorating endoplasmic reticulum (ER) stress and inhibiting apoptosis

PURPOSE: The objective of this study was to examine the effect of tauroursodeoxycholic acid (TUDCA) on intracytoplasmic sperm injection (ICSI) embryos by evaluating endoplasmic reticulum (ER) stress, apoptosis, and embryo developmental competence in vitro and in vivo. METHODS: ER stress–associated g...

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Pubblicato in:J Assist Reprod Genet
Autori principali: Deng, Tengfei, Xie, Juanke, Ge, Hengtao, Liu, Qi, Song, Xiaobing, Hu, Lin, Meng, Li, Zhang, Cuilian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2019
Soggetti:
Assisted Reproduction Technologies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000595/
https://ncbi.nlm.nih.gov/pubmed/31802346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-019-01627-2
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