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Microscopic Characterization of GRP1 PH Domain Interaction With Anionic Membranes

The pleckstrin homology (PH) domain of general receptor for phosphoionositides 1 (GRP1-PHD) binds specifically to phosphatidylinositol (3,4,5)-triphosphate (PIP(3)), and acts as a second messenger. Using an extensive array of molecular dynamics (MD) simulations employing highly mobile membrane mimet...

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Bibliografski detalji
Izdano u:J Comput Chem
Glavni autori: Pant, Shashank, Tajkhorshid, Emad
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000246/
https://ncbi.nlm.nih.gov/pubmed/31762060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.26109
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