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Microscopic Characterization of GRP1 PH Domain Interaction With Anionic Membranes
The pleckstrin homology (PH) domain of general receptor for phosphoionositides 1 (GRP1-PHD) binds specifically to phosphatidylinositol (3,4,5)-triphosphate (PIP(3)), and acts as a second messenger. Using an extensive array of molecular dynamics (MD) simulations employing highly mobile membrane mimet...
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| Publicado no: | J Comput Chem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7000246/ https://ncbi.nlm.nih.gov/pubmed/31762060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.26109 |
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