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Combining Precursor and Fragment Information for Improved Detection of Differential Abundance in Data Independent Acquisition
In bottom-up, label-free discovery proteomics, biological samples are acquired in a data-dependent (DDA) or data-independent (DIA) manner, with peptide signals recorded in an intact (MS1) and fragmented (MS2) form. While DDA has only the MS1 space for quantification, DIA contains both MS1 and MS2 at...
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| Опубликовано в: : | Mol Cell Proteomics |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Biochemistry and Molecular Biology
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7000113/ https://ncbi.nlm.nih.gov/pubmed/31888964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001705 |
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