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Electrosprayed Polymeric Nanospheres for Enhanced Solubility, Dissolution Rate, Oral Bioavailability and Antihyperlipidemic Activity of Bezafibrate

BACKGROUND: Bezafibrate is a BCS class II drug as it presents very low solubility in water; therefore, its bioavailability after oral administration is very poor. The aim of this work was to enhance solubility and dissolution rate of bezafibrate in water in order to enhance its oral bioavailability....

詳細記述

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書誌詳細
出版年:Int J Nanomedicine
主要な著者: Sun, Ru, Shen, Chengwu, Shafique, Shumaila, Mustapha, Omer, Hussain, Talib, Khan, Ikram Ullah, Mehmood, Yasir, Anwer, Khaleeq, Shahzad, Yasser, Yousaf, Abid Mehmood
フォーマット: Artigo
言語:Inglês
出版事項: Dove 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6999775/
https://ncbi.nlm.nih.gov/pubmed/32099359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S235146
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