Electrosprayed Polymeric Nanospheres for Enhanced Solubility, Dissolution Rate, Oral Bioavailability and Antihyperlipidemic Activity of Bezafibrate

BACKGROUND: Bezafibrate is a BCS class II drug as it presents very low solubility in water; therefore, its bioavailability after oral administration is very poor. The aim of this work was to enhance solubility and dissolution rate of bezafibrate in water in order to enhance its oral bioavailability....

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Sun, Ru, Shen, Chengwu, Shafique, Shumaila, Mustapha, Omer, Hussain, Talib, Khan, Ikram Ullah, Mehmood, Yasir, Anwer, Khaleeq, Shahzad, Yasser, Yousaf, Abid Mehmood
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6999775/
https://ncbi.nlm.nih.gov/pubmed/32099359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S235146
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