In-Vitro and In-Vivo Evaluation of Velpatasvir- Loaded Mesoporous Silica Scaffolds. A Prospective Carrier for Drug Bioavailability Enhancement

The limited aqueous solubility of many active pharmaceutical ingredients (APIs) is responsible for their poor performance and low drug levels in blood and at target sites. Various approaches have been adopted to tackle this issue. Most recently, mesoporous silica nanoparticles (MSN) have gained atte...

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Vydáno v:Pharmaceutics
Hlavní autoři: Mehmood, Yasir, Khan, Ikram Ullah, Shahzad, Yasser, Khan, Rizwan Ullah, Iqbal, Muhammad Shahid, Khan, Haseeb Ahmad, Khalid, Ikrima, Yousaf, Abid Mehmood, Khalid, Syed Haroon, Asghar, Sajid, Asif, Muhammad, Hussain, Talib, Shah, Shefaat Ullah
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238066/
https://ncbi.nlm.nih.gov/pubmed/32231052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12040307
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