The Tumor Suppressor, p53, Negatively Regulates Non-Canonical NF-κB Signaling through miRNA-Induced Silencing of NF-κB–Inducing Kinase

NF-κB signaling through both canonical and non-canonical pathways plays a central role in immune responses and inflammation. NF-κB–inducing kinase (NIK) stabilization is a key step in activation of the non-canonical pathway and its dysregulation implicated in various hematologic malignancies. The tu...

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Publicado no:Mol Cells
Main Authors: Jang, Hanbit, Park, Seulki, Kim, Jaehoon, Kim, Jong Hwan, Kim, Seon-Young, Cho, Sayeon, Park, Sung Goo, Park, Byoung Chul, Kim, Sunhong, Kim, Jeong-Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Molecular and Cellular Biology 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6999715/
https://ncbi.nlm.nih.gov/pubmed/31870133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2019.0239
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