Dual-specificity phosphatase 5 acts as an anti-inflammatory regulator by inhibiting the ERK and NF-κB signaling pathways

Although dual-specificity phosphatase 5 (DUSP5), which inactivates extracellular signal-regulated kinase (ERK), suppresses tumors in several types of cancer, its functional roles remain largely unknown. Here, we show that DUSP5 is induced during lipopolysaccharide (LPS)-mediated inflammation and inh...

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Vydáno v:Sci Rep
Hlavní autoři: Seo, Huiyun, Cho, Young-Chang, Ju, Anna, Lee, Sewoong, Park, Byoung Chul, Park, Sung Goo, Kim, Jeong-Hoon, Kim, Kwonseop, Cho, Sayeon
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725455/
https://ncbi.nlm.nih.gov/pubmed/29229953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17591-9
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