TGFB1-induced autophagy affects the pattern of pancreatic cancer progression in distinct ways depending on SMAD4 status

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal malignancies. Given that macroautophagy/autophagy activation is prevalent in PDAC, the dual roles of autophagy could be involved in PDAC heterogeneity. In this work, we demonstrated that TGFB1 induced autophagic flux th...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Liang, Chen, Xu, Jin, Meng, Qingcai, Zhang, Bo, Liu, Jiang, Hua, Jie, Zhang, Yiyin, Shi, Si, Yu, Xianjun
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6999639/
https://ncbi.nlm.nih.gov/pubmed/31177911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1628540
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