TGFB1-induced autophagy affects the pattern of pancreatic cancer progression in distinct ways depending on SMAD4 status

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal malignancies. Given that macroautophagy/autophagy activation is prevalent in PDAC, the dual roles of autophagy could be involved in PDAC heterogeneity. In this work, we demonstrated that TGFB1 induced autophagic flux th...

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Vydáno v:Autophagy
Hlavní autoři: Liang, Chen, Xu, Jin, Meng, Qingcai, Zhang, Bo, Liu, Jiang, Hua, Jie, Zhang, Yiyin, Shi, Si, Yu, Xianjun
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6999639/
https://ncbi.nlm.nih.gov/pubmed/31177911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1628540
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