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GPx1 is involved in the induction of protective autophagy in pancreatic cancer cells in response to glucose deprivation

Given the dense stroma and poor vascularization, access to nutrients is limited in the microenvironment of pancreatic ductal adenocarcinoma (PDA). PDA cells can efficiently recycle various metabolic substrates through the activation of different rescuing pathways, including the autophagy pathway. Ho...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Meng, Qingcai, Xu, Jin, Liang, Chen, Liu, Jiang, Hua, Jie, Zhang, Yiyin, Ni, Quanxing, Shi, Si, Yu, Xianjun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290009/
https://ncbi.nlm.nih.gov/pubmed/30538220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1244-z
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