Bone mesenchymal stem cell-derived exosomal microRNA-29b-3p prevents hypoxic-ischemic injury in rat brain by activating the PTEN-mediated Akt signaling pathway

BACKGROUND: Mesenchymal stem cells (MSCs) are suspected to exert neuroprotective effects in brain injury, in part through the secretion of extracellular vesicles like exosomes containing bioactive compounds. We now investigate the mechanism by which bone marrow MSCs (BMSCs)-derived exosomes harborin...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Hou, Kun, Li, Guichen, Zhao, Jinchuan, Xu, Baofeng, Zhang, Yang, Yu, Jinlu, Xu, Kan
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6998092/
https://ncbi.nlm.nih.gov/pubmed/32014002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-1725-8
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