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Bone mesenchymal stem cell-derived exosomal microRNA-29b-3p prevents hypoxic-ischemic injury in rat brain by activating the PTEN-mediated Akt signaling pathway

BACKGROUND: Mesenchymal stem cells (MSCs) are suspected to exert neuroprotective effects in brain injury, in part through the secretion of extracellular vesicles like exosomes containing bioactive compounds. We now investigate the mechanism by which bone marrow MSCs (BMSCs)-derived exosomes harborin...

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書誌詳細
出版年:J Neuroinflammation
主要な著者: Hou, Kun, Li, Guichen, Zhao, Jinchuan, Xu, Baofeng, Zhang, Yang, Yu, Jinlu, Xu, Kan
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6998092/
https://ncbi.nlm.nih.gov/pubmed/32014002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-1725-8
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