Bone mesenchymal stem cell-derived exosomal microRNA-29b-3p prevents hypoxic-ischemic injury in rat brain by activating the PTEN-mediated Akt signaling pathway

BACKGROUND: Mesenchymal stem cells (MSCs) are suspected to exert neuroprotective effects in brain injury, in part through the secretion of extracellular vesicles like exosomes containing bioactive compounds. We now investigate the mechanism by which bone marrow MSCs (BMSCs)-derived exosomes harborin...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Hou, Kun, Li, Guichen, Zhao, Jinchuan, Xu, Baofeng, Zhang, Yang, Yu, Jinlu, Xu, Kan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6998092/
https://ncbi.nlm.nih.gov/pubmed/32014002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-1725-8
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