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Nucleophosmin1 (NPM1) abnormality in hematologic malignancies, and therapeutic targeting of mutant NPM1 in acute myeloid leukemia

Nucleophosmin (NPM1) is an abundant nucleolar protein that is implicated in a variety of biological processes and in the pathogenesis of several human malignancies. For hematologic malignancies, approximately one-third of anaplastic large-cell non-Hodgkin’s lymphomas were found to express a fusion b...

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Publicat a:Ther Adv Hematol
Autors principals: Chen, Yingyu, Hu, Jianda
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997955/
https://ncbi.nlm.nih.gov/pubmed/32071709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620719899818
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