Intact HIV Proviruses Persist in Children Seven to Nine Years after Initiation of Antiretroviral Therapy in the First Year of Life

In adults starting antiretroviral therapy (ART) during acute infection, 2% of proviruses that persist on ART are genetically intact by sequence analysis. In contrast, a recent report in children treated early failed to detect sequence-intact proviruses. In another cohort of children treated early, w...

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Vydáno v:J Virol
Hlavní autoři: Katusiime, Mary Grace, Halvas, Elias K., Wright, Imogen, Joseph, Kevin, Bale, Michael J., Kirby-McCullough, Bronwyn, Engelbrecht, Susan, Shao, Wei, Hu, Wei-Shau, Cotton, Mark F., Mellors, John W., Kearney, Mary F., van Zyl, Gert U.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997763/
https://ncbi.nlm.nih.gov/pubmed/31776265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01519-19
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