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Base excision repair but not DNA double‐strand break repair is impaired in aged human adipose‐derived stem cells

The decline in DNA repair capacity contributes to the age‐associated decrease in genome integrity in somatic cells of different species. However, due to the lack of clinical samples and appropriate tools for studying DNA repair, whether and how age‐associated changes in DNA repair result in a loss o...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Zhang, Haiping, Cai, Bailian, Geng, Anke, Tang, Huanyin, Zhang, Wenjun, Li, Sheng, Jiang, Ying, Tan, Rong, Wan, Xiaoping, Mao, Zhiyong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996963/
https://ncbi.nlm.nih.gov/pubmed/31782607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13062
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