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Early removal of senescent cells protects retinal ganglion cells loss in experimental ocular hypertension
Experimental ocular hypertension induces senescence of retinal ganglion cells (RGCs) that mimics events occurring in human glaucoma. Senescence‐related chromatin remodeling leads to profound transcriptional changes including the upregulation of a subset of genes that encode multiple proteins collect...
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| Veröffentlicht in: | Aging Cell |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6996954/ https://ncbi.nlm.nih.gov/pubmed/31867890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13089 |
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