Mouse model of ocular hypertension with retinal ganglion cell degeneration

OBJECTIVES: Ocular hypertension is a primary risk factor for glaucoma and results in retinal ganglion cell (RGC) degeneration. Current animal models of glaucoma lack severe RGC cell death as seen in glaucoma, making assessment of physiological mediators of cell death difficult. We developed a modifi...

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Bibliographic Details
Published in:PLoS One
Main Authors: Mukai, Ryo, Park, Dong Ho, Okunuki, Yoko, Hasegawa, Eiichi, Klokman, Garrett, Kim, Clifford B., Krishnan, Anitha, Gregory-Ksander, Meredith, Husain, Deeba, Miller, Joan W., Connor, Kip M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331128/
https://ncbi.nlm.nih.gov/pubmed/30640920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208713
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