Measurement of Oxidatively Induced DNA Damage in Caenorhabditis elegans with High-Salt DNA Extraction and Isotope-Dilution Mass Spectrometry

Caenorhabditis elegans is used extensively as a medical and toxicological model organism. However, little is known about background levels of oxidatively induced DNA damage in the nematode or how culturing methods affect DNA damage levels. The tough C. elegans cuticle makes it challenging to extract...

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Udgivet i:Anal Chem
Main Authors: Scanlan, Leona D., Coskun, Sanem Hosbas, Jaruga, Pawel, Hanna, Shannon K., Sims, Christopher M., Almeida, Jamie L., Catoe, David, Coskun, Erdem, Golan, Rachel, Dizdaroglu, Miral, Nelson, Bryant C.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996937/
https://ncbi.nlm.nih.gov/pubmed/31454479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b01503
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