Identification and Quantification of DNA Repair Protein Apurinic/Apyrimidinic Endonuclease 1 (APE1) in Human Cells by Liquid Chromatography/Isotope-Dilution Tandem Mass Spectrometry

Unless repaired, DNA damage can drive mutagenesis or cell death. DNA repair proteins may therefore be used as biomarkers in disease etiology or therapeutic response prediction. Thus, the accurate determination of DNA repair protein expression and genotype is of fundamental importance. Among DNA repa...

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Main Authors: Kirkali, Güldal, Jaruga, Pawel, Reddy, Prasad T., Tona, Alessandro, Nelson, Bryant C., Li, Mengxia, Wilson, David M., Dizdaroglu, Miral
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726725/
https://ncbi.nlm.nih.gov/pubmed/23922845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069894
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