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Molecular interactions between sex hormone–binding globulin and nonsteroidal ligands that enhance androgen activity
Sex hormone–binding globulin (SHBG) determines the equilibrium between free and protein-bound androgens and estrogens in the blood and regulates their access to target tissues. Using crystallographic approaches and radiolabeled competitive binding-capacity assays, we report here how two nonsteroidal...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6996888/ https://ncbi.nlm.nih.gov/pubmed/31852737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011051 |
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