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Human sex hormone–binding globulin variants associated with hyperandrogenism and ovarian dysfunction

The access of testosterone and estradiol to target tissues is regulated by sex hormone–binding globulin (SHBG) in human blood. Serum SHBG levels are low in patients with hyperandrogenism, especially in association with polycystic ovarian syndrome (PCOS) and in individuals at risk for diabetes and he...

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Detalhes bibliográficos
Main Authors: Hogeveen, Kevin N., Cousin, Patrice, Pugeat, Michel, Dewailly, Didier, Soudan, Benoît, Hammond, Geoffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150924/
https://ncbi.nlm.nih.gov/pubmed/11927624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14060
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