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Synthesis and Antitumor Evaluation of Novel Hybrids of Phenylsulfonylfuroxan and Estradiol Derivatives

Fifteen novel furoxan‐based nitric oxide (NO) releasing hybrids of estradiol derivatives were synthesized and evaluated in vitro anti‐proliferative activity in MDA‐MB‐231, A2780, Hela and HUVEC cell lines. Most of them displayed potent anti‐proliferative effects. Among the compounds, 4‐bromo‐3‐((phe...

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Foilsithe in:ChemistryOpen
Main Authors: Wan, Qi, Deng, Yan, Huang, Yaoqing, Yu, Zhihui, Wang, Chunli, Wang, Ke, Dong, Jibin, Chen, Ying
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996566/
https://ncbi.nlm.nih.gov/pubmed/32025462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201900228
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