Cover Feature: Synthesis and Antitumor Evaluation of Novel Hybrids of Phenylsulfonylfuroxan and Estradiol Derivatives (ChemistryOpen 2/2020)

The Cover Feature shows the novel hybrid of phenylsulfonylfuroxan and estradiol derivative 11b exhibited the best activity with IC(50) values of 3.58‐0.0008 μm against the MDA‐MB‐231, A2780 and Hela cell lines. NO‐releasing capacity and inhibition of ERK/MAPK pathway signaling might explain the pote...

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Publicado en:ChemistryOpen
Main Authors: Wan, Qi, Deng, Yan, Huang, Yaoqing, Yu, Zhihui, Wang, Chunli, Wang, Ke, Dong, Jibin, Chen, Ying
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996563/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.202000011
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