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Synthesis and mechanisms of action of novel harmine derivatives as potential antitumor agents
A series of novel harmine derivatives bearing a benzylindine substituent in position-1 of β-carboline ring were synthesized and evaluated as antitumor agents. The N2-benzylated β-carboline derivatives 3a–g represented the most interesting anticancer activities and compound 3c was found to be the mos...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5021947/ https://ncbi.nlm.nih.gov/pubmed/27625151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33204 |
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