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Apolipoprotein E Genotype Affects Size of ApoE Complexes in Cerebrospinal Fluid

Apolipoprotein E (apoE) is associated with lipoproteins in the cerebrospinal fluid (CSF). APOE4 increases and APOE2 decreases the risk for Alzheimer disease (AD) compared to the risk associated with APOE3 . Because apoE4 is less efficient at cholesterol efflux than apoE2 or apoE3 in vitro , we hypot...

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Pubblicato in:J Neuropathol Exp Neurol
Autori principali: Heinsinger, Nicolette Mary, Gachechiladze, Mariam Alexandra, Rebeck, G. William
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996536/
https://ncbi.nlm.nih.gov/pubmed/27516118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlw067
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