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Phenotypic expansion of autosomal dominant retinitis pigmentosa associated with the D477G mutation in RPE65

Mutations in the gene RPE65 (OMIM: 180069) are recessively inherited and known to cause Leber congenital amaurosis. Recently, the mutation D477G in RPE65 has been identified as a cause of autosomal dominant retinitis pigmentosa (RP). Variable expressivity of this disease has been reported, as carrie...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Mol Case Stud
Main Authors: Jauregui, Ruben, Cho, Ahra, Oh, Jin Kyun, Tanaka, Akemi J., Sparrow, Janet R., Tsang, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996519/
https://ncbi.nlm.nih.gov/pubmed/32014860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a004952
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