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Cellular mechanisms of tumour suppression by the retinoblastoma gene
The retinoblastoma (RB) tumour suppressor gene is functionally inactivated in a broad range of paediatric and adult cancers, and a plethora of cellular functions and partners have been identified for the RB protein. Data from human tumours and studies from mouse models indicate that loss of RB funct...
Gespeichert in:
| Veröffentlicht in: | Nat Rev Cancer |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6996492/ https://ncbi.nlm.nih.gov/pubmed/18650841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2399 |
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