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Calpain‐mediated cleavage of p53 in human cytomegalovirus‐infected lung fibroblasts

Endogenous fragments of p53 protein were identified in human cytomegalovirus (HCMV)‐infected human lung fibroblasts, particularly a 44‐kDa N‐terminal fragment [hereafter referred to as p53(ΔCp44)], generated via calpain cleavage. The fragment abundance increased in a biphasic manner, peaking at 6‐9 ...

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Detalhes bibliográficos
Publicado no:FASEB Bioadv
Main Authors: Chen, Zhenping, Boor, Paul J., Finnerty, Celeste C., Herndon, David N., Albrecht, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996331/
https://ncbi.nlm.nih.gov/pubmed/32123827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.1028
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