P04.81 Calpain 2 mediates ZBTB18 proteolytic cleavage in GBM

BACKGROUND: ZBTB18 (Zinc Finger and BTB Domain Containing 18) is a zing finger transcriptional repressor which plays crucial role in brain development and neuronal differentiation. ZBTB18 is highly expressed in healthy brain but downregulated in glioblastoma (GBM) and GBM cell lines. RESULTS: We hav...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Masilamani, A, Ferrarese, R, Kling, E, Helm, J, Yuan, S, Schilling, O, Carro, M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Poster Presentations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144636/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.315
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