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P04.81 Calpain 2 mediates ZBTB18 proteolytic cleavage in GBM

BACKGROUND: ZBTB18 (Zinc Finger and BTB Domain Containing 18) is a zing finger transcriptional repressor which plays crucial role in brain development and neuronal differentiation. ZBTB18 is highly expressed in healthy brain but downregulated in glioblastoma (GBM) and GBM cell lines. RESULTS: We hav...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Masilamani, A, Ferrarese, R, Kling, E, Helm, J, Yuan, S, Schilling, O, Carro, M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144636/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.315
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