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Reduced chain length in myelin sphingolipids and poorer motor coordination in mice deficient in the fatty acid elongase Elovl1

Very‐long‐chain fatty acids, with a chain length of >C20, are abundant in myelin sphingolipids. Recently, a de novo mutation in the ELOVL1 gene, which encodes fatty acid elongase, was identified in patients with neurocutaneous disorders involving skin ichthyosis and multiple neurological abnormal...

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Detaylı Bibliyografya
Yayımlandı:FASEB Bioadv
Asıl Yazarlar: Isokawa, Masashi, Sassa, Takayuki, Hattori, Satoko, Miyakawa, Tsuyoshi, Kihara, Akio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996318/
https://ncbi.nlm.nih.gov/pubmed/32123819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2019-00067
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