Enhanced Delivery of Rituximab Into Brain and Lymph Nodes Using Timed-Release Nanocapsules in Non-Human Primates

Tumor metastasis into the central nervous system (CNS) and lymph nodes (LNs) is a major obstacle for effective therapies. Therapeutic monoclonal antibodies (mAb) have revolutionized tumor treatment; however, their efficacy for treating metastatic tumors-particularly, CNS and LN metastases-is poor du...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Immunol
Prif Awduron: Qin, Meng, Wang, Lan, Wu, Di, Williams, Christopher K., Xu, Duo, Kranz, Emiko, Guo, Qi, Guan, Jiaoqiong, Vinters, Harry V., Lee, YooJin, Xie, Yiming, Luo, Yun, Sun, Guibo, Sun, Xiaobo, He, Zhanlong, Lu, Yunfeng, Kamata, Masakazu, Wen, Jing, Chen, Irvin S. Y.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996053/
https://ncbi.nlm.nih.gov/pubmed/32047498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03132
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