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Modulation of Gene Expression by Polymer Nanocapsule Delivery of DNA Cassettes Encoding Small RNAs

Small RNAs, including siRNAs, gRNAs and miRNAs, modulate gene expression and serve as potential therapies for human diseases. Delivery to target cells remains the fundamental limitation for use of these RNAs in humans. To address this challenge, we have developed a nanocapsule delivery technology th...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yan, Ming, Wen, Jing, Liang, Min, Lu, Yunfeng, Kamata, Masakazu, Chen, Irvin S. Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452785/
https://ncbi.nlm.nih.gov/pubmed/26035832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127986
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