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AKR1C3 promotes AR-V7 protein stabilization and confers resistance to AR-targeted therapies in advanced prostate cancer
The mechanisms resulting in resistance to next generation anti-androgens in castration resistant prostate cancer are incompletely understood. Numerous studies have determined that constitutively active androgen receptor (AR) signaling or full length AR bypass mechanisms may contribute to the resista...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Cancer Ther |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6995728/ https://ncbi.nlm.nih.gov/pubmed/31308078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-1322 |
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