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The Role of the Ω-Loop in Regulation of the Catalytic Activity of TEM-Type β-Lactamases
Bacterial resistance to β-lactams, the most commonly used class of antibiotics, poses a global challenge. This resistance is caused by the production of bacterial enzymes that are termed β-lactamases (βLs). The evolution of serine-class A β-lactamases from penicillin-binding proteins (PBPs) is relat...
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| Publicado no: | Biomolecules |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6995641/ https://ncbi.nlm.nih.gov/pubmed/31835662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9120854 |
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