The Interplay between Retinal Pathways of Cholesterol Output and Its Effects on Mouse Retina

In mammalian retina, cholesterol excess is mainly metabolized to oxysterols by cytochromes P450 27A1 (CYP27A1) and 46A1 (CYP46A1) or removed on lipoprotein particles containing apolipoprotein E (APOE). In contrast, esterification by sterol-O-acyltransferase 1 (SOAT) plays only a minor role in this p...

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Publicado en:Biomolecules
Autores principales: Petrov, Alexey M., Astafev, Artem A., Mast, Natalia, Saadane, Aicha, El-Darzi, Nicole, Pikuleva, Irina A.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995521/
https://ncbi.nlm.nih.gov/pubmed/31842366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9120867
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