Mechanisms that minimize retinal impact of apolipoprotein E absence

Apolipoprotein E (APOE) is a component of lipid-transporting particles and a recognition ligand for receptors, which bind these particles. The APOE isoform ε2 is a risk factor for age-related macular degeneration; nevertheless, APOE absence in humans and mice does not significantly affect the retina...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Saadane, Aicha, Petrov, Alexey, Mast, Natalia, El-Darzi, Nicole, Dao, Tung, Alnemri, Ahab, Song, Ying, Dunaief, Joshua L., Pikuleva, Irina A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277162/
https://ncbi.nlm.nih.gov/pubmed/30333155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M090043
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