The Interplay between Retinal Pathways of Cholesterol Output and Its Effects on Mouse Retina

In mammalian retina, cholesterol excess is mainly metabolized to oxysterols by cytochromes P450 27A1 (CYP27A1) and 46A1 (CYP46A1) or removed on lipoprotein particles containing apolipoprotein E (APOE). In contrast, esterification by sterol-O-acyltransferase 1 (SOAT) plays only a minor role in this p...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Petrov, Alexey M., Astafev, Artem A., Mast, Natalia, Saadane, Aicha, El-Darzi, Nicole, Pikuleva, Irina A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995521/
https://ncbi.nlm.nih.gov/pubmed/31842366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9120867
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