BCREval: a computational method to estimate the bisulfite conversion ratio in WGBS

BACKGROUND: Whole genome bisulfite sequencing (WGBS) also known as BS-seq has been widely used to measure the methylation of whole genome at single-base resolution. One of the key steps in the assay is converting unmethylated cytosines into thymines (BS conversion). Incomplete conversion of unmethyl...

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Библиографические подробности
Опубликовано в: :BMC Bioinformatics
Главные авторы: Zhou, Junhua, Zhao, Minqiong, Sun, Zefang, Wu, Feilong, Liu, Yucong, Liu, Xianghua, He, Zuping, He, Quanze, He, Quanyuan
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
Предметы:
Methodology Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995172/
https://ncbi.nlm.nih.gov/pubmed/32005131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3334-z
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