A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo

There is a strong need for a new broad-spectrum antiinfluenza therapeutic, as vaccination and existing treatments are only moderately effective. We previously engineered a lectin, H84T banana lectin (H84T), to retain broad-spectrum activity against multiple influenza strains, including pandemic and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Covés-Datson, Evelyn M., King, Steven R., Legendre, Maureen, Gupta, Auroni, Chan, Susana M., Gitlin, Emily, Kulkarni, Vikram V., Pantaleón García, Jezreel, Smee, Donald F., Lipka, Elke, Evans, Scott E., Tarbet, E. Bart, Ono, Akira, Markovitz, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995028/
https://ncbi.nlm.nih.gov/pubmed/31932446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915152117
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados