A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo

There is a strong need for a new broad-spectrum antiinfluenza therapeutic, as vaccination and existing treatments are only moderately effective. We previously engineered a lectin, H84T banana lectin (H84T), to retain broad-spectrum activity against multiple influenza strains, including pandemic and...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Covés-Datson, Evelyn M., King, Steven R., Legendre, Maureen, Gupta, Auroni, Chan, Susana M., Gitlin, Emily, Kulkarni, Vikram V., Pantaleón García, Jezreel, Smee, Donald F., Lipka, Elke, Evans, Scott E., Tarbet, E. Bart, Ono, Akira, Markovitz, David M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995028/
https://ncbi.nlm.nih.gov/pubmed/31932446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915152117
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items