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Single-cell tracking demonstrates copper chaperone Atox1 to be required for breast cancer cell migration
Copper ions are needed for several hallmarks of cancer. However, the involved pathways, mechanisms, and copper-binding proteins are mostly unknown. We recently found that cytoplasmic Antioxidant 1 copper chaperone (Atox1), which is up-regulated in breast cancer, is localized at the lamellipodia edge...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6995000/ https://ncbi.nlm.nih.gov/pubmed/31932435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910722117 |
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