The nutrient sensor OGT regulates Hipk stability and tumorigenic-like activities in Drosophila

Environmental cues such as nutrients alter cellular behaviors by acting on a wide array of molecular sensors inside cells. Of emerging interest is the link observed between effects of dietary sugars on cancer proliferation. Here, we identify the requirements of hexosamine biosynthetic pathway (HBP)...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Wong, Kenneth Kin Lam, Liu, Ta-Wei, Parker, Jessica M., Sinclair, Donald A. R., Chen, Yi-Yun, Khoo, Kay-Hooi, Vocadlo, David J., Verheyen, Esther M.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994980/
https://ncbi.nlm.nih.gov/pubmed/31932432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912894117
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