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A positive feedback loop between Myc and aerobic glycolysis sustains tumor growth in a Drosophila tumor model

Cancer cells usually exhibit aberrant cell signaling and metabolic reprogramming. However, mechanisms of crosstalk between these processes remain elusive. Here, we show that in an in vivo tumor model expressing oncogenic Drosophila Homeodomain-interacting protein kinase (Hipk), tumor cells display e...

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Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Wong, Kenneth Kin Lam, Liao, Jenny Zhe, Verheyen, Esther M
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636907/
https://ncbi.nlm.nih.gov/pubmed/31259690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.46315
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