Integrated lipidomic and transcriptomic analyses identify altered nerve triglycerides in mouse models of prediabetes and type 2 diabetes

Peripheral neuropathy (PN) is a complication of prediabetes and type 2 diabetes (T2D). Increasing evidence suggests that factors besides hyperglycaemia contribute to PN development, including dyslipidaemia. The objective of this study was to determine differential lipid classes and altered gene expr...

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Bibliografski detalji
Izdano u:Dis Model Mech
Glavni autori: O'Brien, Phillipe D., Guo, Kai, Eid, Stephanie A., Rumora, Amy E., Hinder, Lucy M., Hayes, John M., Mendelson, Faye E., Hur, Junguk, Feldman, Eva L.
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2020
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994925/
https://ncbi.nlm.nih.gov/pubmed/31822493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.042101
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