Integrated lipidomic and transcriptomic analyses identify altered nerve triglycerides in mouse models of prediabetes and type 2 diabetes

Peripheral neuropathy (PN) is a complication of prediabetes and type 2 diabetes (T2D). Increasing evidence suggests that factors besides hyperglycaemia contribute to PN development, including dyslipidaemia. The objective of this study was to determine differential lipid classes and altered gene expr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Dis Model Mech
Prif Awduron: O'Brien, Phillipe D., Guo, Kai, Eid, Stephanie A., Rumora, Amy E., Hinder, Lucy M., Hayes, John M., Mendelson, Faye E., Hur, Junguk, Feldman, Eva L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Ltd 2020
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994925/
https://ncbi.nlm.nih.gov/pubmed/31822493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.042101
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