Juvenile murine models of prediabetes and type 2 diabetes develop neuropathy

Peripheral neuropathy (neuropathy) is a common complication of obesity and type 2 diabetes in children and adolescents. To model this complication in mice, 5-week-old male C57BL/6J mice were fed a high-fat diet to induce diet-induced obesity (DIO), a model of prediabetes, and a cohort of these anima...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: O'Brien, Phillipe D., Hinder, Lucy M., Rumora, Amy E., Hayes, John M., Dauch, Jacqueline R., Backus, Carey, Mendelson, Faye E., Feldman, Eva L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
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Resource Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307897/
https://ncbi.nlm.nih.gov/pubmed/30446513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.037374
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