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BTBR ob/ob mice as a novel diabetic neuropathy model: neurological characterization and gene expression analyses

Given the lack of treatments for diabetic neuropathy (DN), a common diabetic complication, accurate disease models are necessary. Characterization of the leptin-deficient BTBR ob/ob mouse, a type 2 diabetes model, demonstrated that the mice develop robust diabetes coincident with severe neuropathic...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: O’Brien, Phillipe D., Hur, Junguk, Hayes, John M., Backus, Carey, Sakowski, Stacey A., Feldman, Eva L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416075/
https://ncbi.nlm.nih.gov/pubmed/25447227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.10.015
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