Dual CCR2/CCR5 antagonist treatment attenuates adipose inflammation, but not microvascular complications in ob/ob mice

Diabetic peripheral neuropathy (DPN) and diabetic kidney disease (DKD) are common diabetic complications with limited treatment options. Experimental studies show that targeting inflammation using chemokine receptor (CCR) antagonists ameliorates DKD, presumably by reducing macrophage accumulation or...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Diabetes Obes Metab
Päätekijät: O’Brien, Phillipe D., Hinder, Lucy M., Parlee, Sebastian D., Hayes, John M., Backus, Carey, Zhang, Hongyu, Ma, Lijun, Sakowski, Stacey A., Brosius, Frank C., Feldman, Eva L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610585/
https://ncbi.nlm.nih.gov/pubmed/28332276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.12950
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