Biphasic Role of Tgf-β Signaling during Müller Glia Reprogramming and Retinal Regeneration in Zebrafish

Tgf-β signaling is a major antiproliferative pathway governing different biological functions, including cellular reprogramming. Upon injury, Müller glial cells of zebrafish retina reprogram to form progenitors (MGPCs) essential for regeneration. Here, the significance of Tgf-β signaling for inducin...

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Udgivet i:iScience
Main Authors: Sharma, Poonam, Gupta, Shivangi, Chaudhary, Mansi, Mitra, Soumitra, Chawla, Bindia, Khursheed, Mohammad Anwar, Saran, Navnoor Kaur, Ramachandran, Rajesh
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994856/
https://ncbi.nlm.nih.gov/pubmed/32004993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.100817
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